LONDON — The British government said Prime Minister Boris Johnson would begin a long-anticipated shake-up of his cabinet on Wednesday in a move designed to revitalize a government whose popularity now appears to be waning.

Much speculation about cabinet changes in recent weeks has focused on the foreign secretary, Dominic Raab, whose position has been considered tenuous after widespread criticism of his handling of the evacuation from Afghanistan. His standing was further diminished by his decision to delay returning from vacation as the Taliban took control of Kabul.

Downing Street confirmed the shake-up in a statement but did not provide any further details. “The Prime Minister will today conduct a reshuffle to put in place a strong and united team to build back better from the pandemic,” a spokesman said.

A reshuffle would give Mr. Johnson the chance to reshape the top echelons of his government ahead of a party conference next month at which he will try to provide a clearer post-Covid policy agenda. But with coronavirus case numbers still high, the government is also bracing for the possibility of a surge in hospitalizations in the fall and winter.

On Tuesday, Mr. Johnson laid out his plans for combating the virus as the winter approaches, saying Britain would offer vaccine booster shots to people aged 50 and over, and first shots to children of ages 12 to 15. His government is determined to avoid a further lockdown but could resort to measures like mask mandates if infections surge.

After a successful beginning to Britain’s vaccine program earlier this year, Mr. Johnson’s Conservatives surged in the opinion polls, but that lead now appears to be evaporating. Last week Mr. Johnson took a gamble by breaking an election promise not to raise taxes so that he could allocate more cash to health and social care.

His critics have also complained of a lack of clarity over the government’s main domestic promise of “leveling up,” meaning delivering prosperity to economically deprived regions.

Senior ministers who have faced criticism include the education secretary, Gavin Williamson; the home secretary, Priti Patel, whose department is responsible for policing and immigration; and the housing, communities and local government secretary, Robert Jenrick.

But up to now Mr. Johnson had been reluctant to move or fire members of a top team that was initially selected largely from his own supporters and advocates of Brexit, which Mr. Johnson championed.

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